Author
University of EdinburghORCID 0000-0003-0391-0352Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Emily R. Webb, A. R. S. Black, Giovana Carrasco…·Valerie G. Brunton
This study shows that systemic FAK inhibition reduces immunosuppressive macrophages in glioblastoma by blocking monocyte trafficking, enhancing T cell activity and improving survival in a mouse model.
Dominik Grabarczyk, Mikołaj Kocikowski, Maciej Parys…·Shay B. Cohen
DoggifAI translates non-canine antibody sequences into canine ones using a transformer model, generating species-appropriate framework regions and preserving binding specificity.
Piyali Ganguli, Celia De Los Angeles Colomina Basanta, Amelia Acha‐Sagredo…·Jo Spencer
The paper investigates how CDKN2A and other 9p21 gene losses influence oesophageal cancer progression, finding context-dependent effects on survival and immune infiltration.
J. Robert O’Neill, Marcos Yébenes Mayordomo, Goran Mitulović…·Javier A. Alfaro
The paper identifies GPA33 as an EAC-specific biomarker and reveals post-transcriptional regulation of protein expression in EAC through multi-omics integration.
Georges Bedran, Tongjie Wang, Dominika Pankanin…·Javier A. Alfaro
The paper develops COD-dipp to map MHC Class I antigens from cancer studies and identifies immune-relevant genomic regions for vaccine design.
Sam Abujudeh, Sebastian S. Zeki, MCV van Lanschot…·Richard Calvin Turkington
The paper introduces conliga, a method for inferring high-resolution SCNA profiles from a low-cost and simple assay, addressing the need for affordable SCNA analysis in clinical settings.