Johanna Denkena

This study shows translocations can drive widespread gene expression changes across entire chromosome arms in MCL by altering chromatin organization and regulatory loops.

AlphaBeta estimates epimutation rates and spectra from DNA methylation data in plants, showing conserved epimutation landscapes and providing a molecular clock for tree age-dating.

The paper quantifies age-related somatic mutations and epimutations in a wild Populus trichocarpa tree over 330 years, showing lower mutation rates than annuals and distinct epimutation origins.