Nathan E. Wineinger

AoUPRS provides a cost-effective PRS calculator for the All of Us dataset, offering both dense and sparse approaches with comparable predictive power.

This study evaluates the impact of coronary artery disease polygenic risk scores on lipid-lowering therapy initiation via a mobile application, finding higher therapy rates among high-risk individuals.

This study identifies 26 genetic loci associated with physical activity using UK Biobank data, including APOE and CADM2, and finds genetic correlations with educational attainment and psychiatric traits.

The paper introduces a mobile app, MyGeneRank, that provides individuals with their genomic risk of coronary artery disease to inform lifestyle and medication decisions.

The paper introduces RASLseqTools, an open-source software package for designing and analyzing RASL-seq experiments, and demonstrates normalization methods for improving reproducibility.