BiophysicsbioRxivPreprint
High-throughput affinity measurements of direct interactions between activation domains and co-activators
Nicole V. DelRosso, Peter Suzuki, Daniel Griffith…·Polly Morrell Fordyce
This study quantifies direct interactions between 204 human activation domains and eight co-activators using a microfluidic platform, revealing 334 novel binding pairs and demonstrating the utility of analytical models for predicting activation.
22 citations