Author

Chew Leng Lim

Nanyang Technological UniversityORCID 0000-0003-4529-2732Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Valerie C. L. LiniD· 2 shared Amanda Rui En WooiD· 1 shared Bernett Lee Teck Kwong· 1 shared Feng LiniD· 1 shared Hirohito Hayashi· 1 shared Hwa Hwa Chung· 1 shared Jace KohiD· 1 shared Pheck Khee Lau· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Valerie C. L. LinORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 23, 2025

Methylation mimic mutations of progesterone receptor AF1 impair gene-specific regulation through stabilized chromatin interactions

Pheck Khee Lau, Bernett Lee Teck Kwong, Shi Hao Lee…·Valerie C. L. Lin

This study shows that methylation mimic mutations in PR AF1 alter gene-specific regulation by affecting chromatin interactions and coregulator binding in breast cancer cells.

DOI 10.1101/2025.10.23.684277

humanDNA methylation

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Developmental BiologyeLifePeer-reviewedJul 24, 2020

Estrogen exacerbates mammary involution through neutrophil dependent and independent mechanism

Chew Leng Lim, Yu Zuan Or, Zoe Ong…·Valerie C. L. Lin

This study shows estrogen promotes mammary involution by enhancing inflammation, cell death, and adipocyte repopulation through both neutrophil-dependent and -independent mechanisms.

31 citations

mousebulk RNA-seq

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