Developmental BiologybioRxivPreprint
mTOR regulates Wnt signaling to promote tension-mediated lens vesicle closure
Qian Wang, Hao Wu, Yingyu Mao…·Xin Zhang
This study identifies an mTOR-Wnt-Rac1 signaling axis that regulates cytoskeletal tension to drive lens vesicle closure, with disruptions leading to developmental defects like Peters anomaly.
DOI 10.1101/2025.02.24.639869