Author

Riku Katainen

University of HelsinkiORCID 0000-0003-4575-4239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:whole-genome sequencing· 4 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:whole-exome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Lauri A. AaltoneniD· 4 shared Esa PitkäneniD· 3 shared Eevi KaasineniD· 2 shared Kimmo PaliniD· 2 shared Tatiana CajusoiD· 2 shared Adam P GiessiD· 1 shared Afshan SiddiqiD· 1 shared Alexander StuckeyiD· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersGenomics

Lauri A. AaltonenORCID

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4 papers

Recent·Most cited

Mutation-Attention (MuAt): deep representation learning of somatic mutations for tumour typing and subtyping

Prima Sanjaya, Katri Maljanen, Riku Katainen, Sebastian M. Waszak, John C. Ambrose, P. Arumugam, Roel P. J. Bevers, Marta Bleda, F. Boardman-Pretty, Christopher R. Boustred, Helen K. Brittain, Matthew Arthur Brown, Mark J. Caulfield, G. C. Chan, Adam P Giess, , Esa Pitkänen

The paper introduces MuAt, a deep learning model that learns representations of somatic mutations to predict tumour types and subtypes with high accuracy.

Genome Medicine · Jul 7, 2023Peer-reviewedGenomics

Mutational processes of distinct POLE exonuclease domain mutants drive an enrichment of a specific TP53 mutation in colorectal cancer

Fang Hu, Jayne A. Barbour, Rebecca C. Poulos, Riku Katainen, Lauri A. Aaltonen, Jason W.H. Wong

The paper analyzes POLE exonuclease domain mutants in colorectal cancer, identifying mutation spectra differences and a specific TP53 mutation enrichment.

PLoS Genetics · Feb 3, 2020Peer-reviewedGenomics

Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival

Tatiana Cajuso, Päivi Sulo, Tomas J. Tanskanen, Riku Katainen, Aurora Taira, Ulrika A. Hänninen, Johanna Kondelin, Linda M. Forsström, Niko Välimäki, Mervi Aavikko, Eevi Kaasinen, Ari P. Ristimaki, Selja Koskensalo, Anna Lepistö, Laura Renkonen‐Sinisalo, , Lauri A. Aaltonen

This study identifies retrotransposon insertions in colorectal tumors, linking them to cancer initiation and poor patient survival.

Nature Communications · Sep 6, 2019Peer-reviewedGenomics

BasePlayer: Versatile Analysis Software For Large-Scale Genomic Variant Discovery

Riku Katainen, Iikki Donner, Tatiana Cajuso, Eevi Kaasinen, Kimmo Palin, Veli Mäkinen, Lauri A. Aaltonen, Esa Pitkänen

BasePlayer is a software tool for analyzing large-scale NGS data, enabling variant analysis, visualization, and integration of genomic data.

bioRxiv · Apr 11, 2017 · PreprintBioinformatics