Author

Megan R. Kiedrowski

University of Alabama at BirminghamORCID 0000-0003-4610-182XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Assay:proteomics· 1

Frequent Co-Authors

Caitlyn C. SebastianiD· 2 shared Abigail N. RobertsoniD· 1 shared Ayisha ZiaiD· 1 shared Fengbin WangiD· 1 shared Gregory G. AndersoniD· 1 shared Hua ZhangiD· 1 shared Hui Wu· 1 shared Jessie Lynda FieldsiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersMicrobiology

Caitlyn C. SebastianORCID

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3 papers

Recent·Most cited

MicrobiologyCell ReportsPeer-reviewedOct 1, 2026

The archaic CUP pilus SMF-1 uses an antiparallel bundling mechanism to initiate biofilm formation

Jessie Lynda Fields, Caitlyn C. Sebastian, Hua Zhang…·Fengbin Wang

This study reveals the structure and bundling mechanism of SMF-1, a CUP pilus in Stenotrophomonas maltophilia, showing it forms antiparallel bundles that initiate biofilm formation.

DOI 10.1016/j.celrep.2026.118075

bacteria (other)cryo-EM

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MicrobiologyInfection and ImmunityPeer-reviewedJun 4, 2026

Increased Low Molecular Weight Mucins in Muco-Obstructive Airway Disease Limit Staphylococcus aureus Growth

Caitlyn C. Sebastian, RaNashia L. Boone, Susan E. Birket, Megan R. Kiedrowski

This study shows low molecular weight mucins in muco-obstructive airway diseases suppress Staphylococcus aureus growth and biofilm formation, while high molecular weight mucins do not, suggesting species-specific interactions.

DOI 10.1128/iai.00693-25

humanbulk RNA-seq

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MicrobiologyJournal of BacteriologyPeer-reviewedAug 14, 2025

Staphylococcus aureus Phenol-Soluble Modulins Mediate Interspecies Competition with Upper Respiratory Commensal Bacteria

Joshua T. Huffines, Megan R. Kiedrowski

This study identifies S. aureus δ-toxin as a secreted factor that inhibits aggregation and adherence of URT commensals, contributing to microbial dysbiosis in CRS.

6 citations

humanproteomics

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