Author

Shijie Yao

Joint Genome InstituteORCID 0000-0003-4648-5464Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:benchmarking· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Christopher J. SedlacekiD· 1 shared Chuan CaoiD· 1 shared Cuiting Zhong· 1 shared Daniel Barich· 1 shared Derek N. MackliniD· 1 shared Dongwan KangiD· 1 shared Frederik SchulziD· 1 shared Guoqing LiuiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Christopher J. SedlacekORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 17, 2026

Reconstructing sequence-grammar trajectories enables interpretable and tunable cis-regulatory element design

Mingqian Ma, Wanjuan Bu, Guoqing Liu…·Zeyu Chen

This paper introduces GO-CRE, a method for designing cell-type-specific cis-regulatory elements by reconstructing sequence-grammar trajectories and using reinforcement learning with predictor guidance.

DOI 10.64898/2026.07.10.737719

humanDNA methylation

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BioinformaticsbioRxivPreprintNov 9, 2019

A new method for rapid genome classification, clustering, visualization, and novel taxa discovery from metagenome

Zhong Wang, Harrison Ho, Rob S Egan…·Joan L. Slonczewski

Genome Constellation improves taxa assignment and discovers novel taxa in metagenomic datasets by clustering genomes based on k-mer similarities.

5 citations

metagenomicsstatistical model

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