Author

Seandean L. Harwood

Aarhus UniversityORCID 0000-0003-4654-8832Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Ana V. AlmeidaiD· 1 shared Birthe Brandt KragelundiD· 1 shared Emil E. TranchantiD· 1 shared Gregers Rom AnderseniD· 1 shared Heidi Gytz OleseniD· 1 shared Henrik PederseniD· 1 shared Ida B. Thøgersen· 1 shared Jan J. EnghildiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ana V. AlmeidaORCID

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1 paper

Recent·Most cited

BiochemistryNature Structural & Molecular BiologyPeer-reviewedJan 23, 2025

Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring

Trine Amalie Fogh Gadeberg, Martin Høgholm Jørgensen, Heidi Gytz Olesen…·Gregers Rom Andersen

This study uses cryo-EM to analyze the structural changes in C3 during hydrolysis, revealing a dynamic opening in the macroglobulin ring that allows domain translocation.

7 citations

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