Jan J. Enghild

The paper identifies new female fecundity factors required for sperm sex peptide binding by analyzing the impact of Abdominal-B loss in Drosophila secondary cells on seminal fluid composition and female response.

This study shows that oral pathogens Porphyromonas gingivalis and Tannerella forsythia use surface-attached proteases to alter the renin-angiotensin system by generating Ang 1-7.

The paper identifies a distinct BAM complex in Bacteroidetes using structural biology and proteomics, revealing an expanded role compared to Proteobacteria.

This study shows that Tannerella forsythia's miropin inhibits Porphyromonas gingivalis proteases, reducing its virulence and challenging Tf's role as a pathogen.

This study uses cryo-EM to analyze the structural changes in C3 during hydrolysis, revealing a dynamic opening in the macroglobulin ring that allows domain translocation.

This paper investigates how PTX3's quaternary structure enables HA crosslinking via interactions with HC1, revealing pH-dependent binding and structural flexibility.

This study chemically modifies HA oligosaccharides to differentially modulate their binding to HABPs, revealing structural insights into HA-receptor interactions.

This study uses transgenic porcine models to show that APP and its AICD domain modulate AD-related gene networks through interactions with signaling proteins.

This paper shows that FICD's adenylyltransferase activity induces ER stress and that its disulfide-bond formation modulates its activity in the context of a hyperactive mutant.