Sylvie Mazan

This study integrates genomic, transcriptomic, and morphological data from the small-spotted catshark to uncover molecular mechanisms underlying sensory organ evolution in jawed vertebrates.

This study identifies ancient Wnt-dependent habenular asymmetries in sharks, suggesting a conserved developmental mechanism across jawed vertebrates.

This study presents a single-nucleus RNA-sequencing atlas of the postnatal shark retina, identifying 22 cell types and providing insights into retinal evolution.

The paper generates a spatial RNA profile of catshark habenulae, identifies novel markers, and reveals asymmetry and organizational patterns, providing a reference for studying habenula evolution in jawed vertebrates.

This study traces the evolutionary origin of OCT4/POU5 functions in supporting pluripotency across vertebrates using sequence analysis and functional studies in mouse ESCs.

This study examines the evolution of lbx gene expression and function in the spinal cord across vertebrates, showing conservation of lbx1 and novel patterns in zebrafish lbx1b and lbx2.

The paper investigates neurogenesis in adult catshark retinas, finding reduced proliferation and neurogenesis compared to juveniles, supported by histological and RNA-Seq analyses.

The paper identifies differential expression patterns of five prosomatostatin genes in the catshark central nervous system using in situ hybridization and immunohistochemistry.

This study characterizes neurogenic niches in the telencephalon of juvenile and adult sharks using immunohistochemical markers, identifying distinct cell subtypes involved in neurogenesis.

This study shows that posterior growth in vertebrates does not generate additional tissue volume but instead relies on tissue deformation and volumetric growth in segmented regions, with differential contributions across species.