Jake Leyhr

This study reconstructs the evolutionary history of the Prox gene family in vertebrates, revealing lineage-specific gene losses and identifying a fourth ancestral Prox gene.

The paper identifies specialized high-capacity mitochondria in C. elegans anchor cells that generate elevated ATP to fuel basement membrane invasion.

The paper catalogs endogenously tagged proteins in C. elegans, identifies gaps in coverage, and provides a database with tools for designing knock-in experiments.

This study integrates genomic, transcriptomic, and morphological data from the small-spotted catshark to uncover molecular mechanisms underlying sensory organ evolution in jawed vertebrates.

This study investigates the first intercostal ligament (ICL1) in zebrafish, proposing its role in stabilizing the Weberian apparatus by minimizing non-optimal movement.

This study identifies a conserved Nkx3.2 enhancer in zebrafish that regulates jaw joint development and shows its functional conservation across gnathostomes.

This study uses CRISPR/Cas9 to knock out nkx3.2 in zebrafish, revealing skeletal phenotypes that suggest conserved ancestral roles in axial skeleton development.

This study investigates the role of Gdf5 in zebrafish fin endoskeleton development, showing its importance in segmentation and structure, with effects increasing from anterior to posterior.