Author

Guanhui Wu

University of Colorado BoulderORCID 0000-0003-4659-8717Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

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Arthur J. ZaugiD· 1 shared John L. RinniD· 1 shared Mingfeng LiuiD· 1 shared Thomas R. CechiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Arthur J. ZaugORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintOct 30, 2026

Impaired synthesis of both telomere strands and adaptive TERT reduction in RTEL1 ATPase-dead cells

Guanhui Wu, Mingfeng Liu, Arthur J. Zaug…·Thomas R. Cech

This study shows RTEL1 ATPase activity is essential for both telomere strand synthesis and TERT regulation, with reduced TERT providing an adaptive survival mechanism in RTEL1-defective cells.

DOI 10.64898/2026.07.23.740398

humanexperimental assay

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