Primary bovine embryonic fibroblasts support seasonal influenza A virus infection and demonstrate variable fitness of HPAI H5N1
Grace K. Wenger, Deann Teresa Snyder, Justin R. Prigge, Allyson H Turner, Sara A Jaffrani, Edward E. Schmidt, Emily A. Bruce, Emma Kate Loveday
This study uses primary bovine embryonic fibroblasts to investigate HPAI H5N1 infection dynamics and finds increased viral fitness in bovine-origin strains and bovine susceptibility to human seasonal IAV.
bioRxiv · Jul 26, 2025 · PreprintMicrobiology