Ibra Seaphus Fancher

This study shows that a single-point mutation in Kir2.1 channels protects mice from diet-induced obesity by altering fat distribution and increasing energy expenditure.

This study shows Kir2.1 channels link flow-induced signaling to Piezo1/PI3K/Akt1 pathways, restoring flow-induced vasodilation in Kir2.1-deficient endothelium.

This study identifies a TRPC6 mutation that protects mice from acute lung injury by promoting endothelial regeneration and preventing vascular injury.