Benjamin A. Doran

This study identifies conserved spatial structures in tumors that predict immune response, using a classification framework based on transcriptional covariation.

The paper shows that cellular adaptability is shaped by evolutionary history through a prioritization hierarchy of transcriptional responses to environmental cues.

The paper describes bacterial strains in the human gut using a statistical model based on their evolutionary history to predict metabolic phenotypes and engineer consortia.

The paper uses single-cell RNA-sequencing to study environmental enteropathy, identifying epithelial and immune correlates of disease severity and suggesting new therapeutic targets.