Dianfan Li

This study profiles early hepatocellular carcinomas to reveal molecular mechanisms of malignancy transition, identifying TERT alterations, CNA burden, and immune evasion as key factors.

The paper identifies and characterizes a nanobody, Sb32, that binds thermostable GFP (TGP) with nanomolar affinity and reveals an unusual binding mechanism involving CDR2 and hydration networks.

This study designs covalent nanobody binders for a thermostable GFP by using structural insights to create disulfide bonds that enhance binding stability.

This study determines the structure of human AQP7 and shows how its unique features enable glycerol transport.