Author

Chen Xie

National Heart Centre SingaporeORCID 0000-0003-4738-2117Unclaimed ORCID profile · follow to get notified of new preprints

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Chen Xie2 papers · Peking University

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Anissa Anindya WidjajaiD· 2 shared Chee Jian PuaiD· 2 shared Jessie Tan· 2 shared Sebastian SchäferiD· 2 shared Sivakumar ViswanathaniD· 2 shared Sonia Pankaj ChothaniiD· 2 shared Stuart A. CookiD· 2 shared Wei‐Wen LimiD· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Anissa Anindya WidjajaORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 9, 2023

Inhibition of an immunometabolic axis of mTORC1 activation extends mammalian healthspan

Anissa Anindya Widjaja, Wei‐Wen Lim, Sivakumar Viswanathan…·Stuart A. Cook

This study shows that inhibiting IL11 improves healthspan in aged mice by reversing metabolic dysfunction, sarcopenia, and frailty.

3 citations

mouseexperimental assay

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Molecular BiologyScience Translational MedicinePeer-reviewedSep 25, 2019

IL-11 is a therapeutic target in idiopathic pulmonary fibrosis

Benjamin Ng, Jinrui Dong, Giuseppe Alessandro D’Agostino…·Stuart A. Cook

The paper identifies IL-11 as a therapeutic target in idiopathic pulmonary fibrosis by showing its role in fibroblast activation and fibrosis progression across species.

314 citationstop 1%

mousebulk RNA-seq

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