NeuroscienceNature CommunicationsPeer-reviewed
Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans
Zachary P. Rosenthal, Joseph B. Majeski, Ala Somarowthu…·Ethan M. Goldberg
This study shows that electroconvulsive therapy (ECT) induces a postictal wave of spreading depolarization in both mice and humans, suggesting a new mechanism for its therapeutic effects.