Author

Britta E. Lindquist

Gladstone InstitutesORCID 0000-0002-7913-9034Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:electronic health records· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Jeanne T. PaziD· 2 shared Yuliya VoskobiynykiD· 2 shared Ala SomarowthuiD· 1 shared Antoneta KarajiD· 1 shared Arjun G. YodhiD· 1 shared C. William ShuttleworthiD· 1 shared Chris AbbottiD· 1 shared Christopher G. FavillaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Jeanne T. PazORCID

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Author profile →

3 papers

Recent·Most cited

Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans

Zachary P. Rosenthal, Joseph B. Majeski, Ala Somarowthu, Davin K. Quinn, Britta E. Lindquist, Mary E. Putt, Antoneta Karaj, Christopher G. Favilla, Wesley B. Baker, Golkoo Hosseini, Jenny P. Rodriguez, Mario A. Cristancho, Yvette I. Sheline, C. William Shuttleworth, Chris Abbott, , Ethan M. Goldberg

This study shows that electroconvulsive therapy (ECT) induces a postictal wave of spreading depolarization in both mice and humans, suggesting a new mechanism for its therapeutic effects.

Nature Communications · May 18, 2025Peer-reviewedNeuroscience

Mapping general anesthesia states based on electro-encephalogram transition phases

Virginie Loison, Yuliya Voskobiynyk, Britta E. Lindquist, Deanna Necula, Dan Longrois, Jeanne T. Paz, David Holcman

The paper develops an algorithm to predict general anesthesia overdose by analyzing EEG transition phases in mice, identifying key patterns that anticipate overdose several minutes in advance.

NeuroImage · Dec 20, 2023Peer-reviewedNeuroscience

Electrobehavioral phenotype and seizure pharmacosensitivity in a novel mouse model of patient-derived SLC6A1 S295L mutation-associated neurodevelopmental epilepsy

Britta E. Lindquist, Yuliya Voskobiynyk, Kimberly Goodspeed, Jeanne T. Paz

This paper describes a novel mouse model of SLC6A1 mutation-associated neurodevelopmental epilepsy, showing seizure burden correlates with behavioral deficits and drug responses.

Epilepsia · Jul 28, 2023Peer-reviewedNeuroscience