The developing retina undergoes mitochondrial remodeling via PINK1/PRKN-dependent mitophagy
Juan Zapata‐Muñoz, Juan Ignacio Jiménez‐Loygorri, Michael Stumpe, Beatriz Villarejo‐Zori, Sandra Alonso‐Gil, Petra Terešak, Benan John Mathai, Ian G. Ganley, Anne Simonsen, Jörn Dengjel, Patricia Boya
The paper identifies two mitophagy peaks during retinal development, one PINK1-independent and one PINK1-dependent, linked to oxidative stress and RGC differentiation.
Journal of Molecular Biology · Jun 3, 2025Peer-reviewedDevelopmental Biology