Dan Goldowitz

In 14 BXD mouse strains, those modelling developmental coordination disorder have relatively larger cortex and smaller cerebellar/subcortical volumes; this axis tracks motor coordination but maps to no single QTL.

This paper identifies Mysm1 mutations as the cause of meander tail mouse cerebellum malformation and links them to hematological and neurological defects.

The paper identifies a novel subset of cerebellar nuclei neurons in mice that originate from an extrinsic germinal zone, distinct from the rhombic lip and ventricular zone.

The paper identifies the spatiotemporal expression patterns of Msx genes in the developing cerebellar neuroepithelium and shows their distinct localization in progenitor zones.

This study identifies dynamic enhancer activity in the mouse cerebellum during development, discovers novel regulators, and links enhancers to autism-related variants.

This study uses QTL analysis in BXD mice to identify genetic loci associated with motor coordination traits similar to human DCD.

This study uses BXD mice and QTL analysis to identify genetic factors linked to motor learning traits resembling developmental coordination disorder.

The paper identifies Pou3f1 as a marker for a previously unrecognized subtype of glutamatergic cerebellar nuclear neurons that follow a distinct transcriptional program compared to the canonical Atoh1-Pax6-Tbr1 pathway.