Author

Charles P. McSharry

NHS Greater Glasgow and ClydeORCID 0000-0003-4758-9038Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

Aziza ElmesmariiD· 3 shared Domenico SommaiD· 3 shared Jack FrewiD· 3 shared Lucy MacDonaldiD· 3 shared Mariola Kurowska‐StolarskaiD· 3 shared Stefano AliverniniiD· 3 shared Theodoros SimakouiD· 3 shared Clara Di MarioiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Aziza ElmesmariORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 29, 2025

The ontogeny of myeloid-stromal synovial tissue niches in rheumatoid arthritis.

Aziza Elmesmari, Domenico Somma, Lucy MacDonald…·Mariola Kurowska‐Stolarska

This study shows human synovial tissue-resident macrophages develop from monocytes guided by fibroblast-derived cues in specific spatial niches, using a novel organoid system.

4 citations

humanscRNA-seq

𝕏 PostBluesky

Cell BiologyDiscovery ImmunologyPeer-reviewedJan 1, 2025

PROS1 released by human lung basal cells upon SARS-CoV-2 infection facilitates epithelial cell repair and limits inflammation.

Theodoros Simakou, Agnieszka M. Szemiel, Lucy MacDonald…·Mariola Kurowska‐Stolarska

This study shows that PROS1 released by lung basal cells during SARS-CoV-2 infection reduces inflammation, promotes epithelial repair, and enhances antigen presentation.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyImmunityPeer-reviewedNov 27, 2024

Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid Arthritis

Lucy MacDonald, Aziza Elmesmari, Domenico Somma…·Mariola Kurowska‐Stolarska

This study identifies distinct myeloid DC subsets in synovial tissue across health and RA states, showing their roles in inflammation and tolerance.

69 citationstop 1%

humanscRNA-seq

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