Rhizobial enzyme reveals pH-driven catalytic switching and ʟ-amino acid incorporation by ʟ,-transpeptidases
Brooks J. Rady, Raj Bahadur, Caroline A. Evans, Stéphane Mesnage
This study characterizes LdtRj8, an LDT enzyme from Rhizobium johnstonii, showing pH-dependent activity and broad amino acid substrate specificity, which may explain muropeptide isomerism and bacterial adaptation to acidic environments.