Graham P. Stafford

The paper characterizes ORF11, a tail-spike lysin from E. faecium Minhovirus, revealing its dual peptidoglycan hydrolysis activity through structural and biochemical analysis.

This study identifies clofarabine as an inhibitor of EPEC pathogenesis by targeting bacterial and host translation, revealing a bacterial mechanism to counteract its effects.

This study identifies 33 distinct domain architectures of prophage endolysins from enterococci, including a novel cell wall-binding domain, to expand the diversity of potential enzybiotics against multidrug-resistant infections.

This paper introduces plaque-2-sequence, a low-cost, high-throughput method for sequencing phage genomes directly from plaques, enabling rapid and scalable genomic analysis of phages.

This study determines the structure of the Enterococcal Polysaccharide Antigen (EPA) from E. faecalis and explores its role in immune evasion and phage susceptibility.