Cell BiologybioRxivPreprint
GCN5-TADA2B in the SAGA complex provide constitutive fine-tuning control of XRCC1 recruitment and focal retention at DNA damage sites.
Keeeun Kim, Junyoung Kim, D. H. T. Lee…·Youngsoo Lee
This study identifies GCN5 and TADA2B as novel XRCC1 binding partners that regulate its recruitment and retention at DNA damage sites, revealing a dual regulatory mechanism in DNA repair.
DOI 10.1101/2025.08.24.672030