Erik Wernersson

This study shows translocations can drive widespread gene expression changes across entire chromosome arms in MCL by altering chromatin organization and regulatory loops.

The paper identifies trans-contacting intronic RNAs (TIRs) in neuronal cells that form nuclear scaffolds called introsomes, influencing 3D genome organization and gene expression.

This study demonstrates that HDAC3's repressor and activator functions can be genetically separated in Drosophila, revealing distinct roles for catalytic activity and SMRTER interaction in transcriptional regulation.

BLISS quantifies DNA double-strand breaks in situ with high sensitivity and efficiency, showing Cpf1 has higher specificity than Cas9.