Gal Markel

This paper develops and tests Anti-4CB1, an anti-HVEM monoclonal antibody, showing enhanced anti-tumor activity in vitro and in vivo, particularly when combined with Anti-PD1, and correlates HVEM expression with treatment response.

Peptriever uses a bi-encoder transformer model to efficiently rank proteins interacting with peptides, achieving high AUC-ROC and AUC-PR scores.

The paper analyzes the structural changes in the SARS-CoV-2 spike protein induced by ACE2 binding, identifying key conformational shifts and their implications for viral entry and therapeutic targeting.