Yui Tik Pang

Nesso-1 is an open-source binding affinity prediction tool that is significantly faster than Boltz-2 while maintaining or improving accuracy on both in-distribution and out-of-distribution data.

DeepPath predicts protein transition pathways using physics-based deep learning, achieving accurate results faster than molecular dynamics simulations.

The paper shows that phosphorylation of the yeast Gγ subunit Ste18 at multiple sites modulates its structure and affects MAPK activation.