Molecular BiologybioRxivPreprint
Nesso-1: Accelerating Open-Source Binding Affinity Predictions
Nikhil Shenoy, David Errington, Emmanuel Bengio…·Francesco Di Giovanni
Nesso-1 is an open-source binding affinity prediction tool that is significantly faster than Boltz-2 while maintaining or improving accuracy on both in-distribution and out-of-distribution data.
DOI 10.64898/2026.08.01.742196