Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
A structure-based mechanism for initiation of AP-3 coated vesicle formation
Matthew Begley, Mahira F. Aragon, Richard W. Baker
This study determines the structural mechanism of AP-3 membrane recruitment and activation through cryo-EM, revealing conformational changes driven by Arf1 binding and cargo engagement.
15 citations