Author

Mahira F. Aragon

New York Structural Biology CenterORCID 0000-0002-0004-6514Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Organism:E. coli· 1 Assay:electronic health records· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Joshua H. MendeziD· 2 shared Alex J. NobleiD· 1 shared Anjelique Sawh-GopaliD· 1 shared Aygul IshemgulovaiD· 1 shared Behrouz Ghazi EsfahaniiD· 1 shared Edward T. EngiD· 1 shared Eugene Y. D. ChuaiD· 1 shared Hui Alex WeiiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Joshua H. MendezORCID

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3 papers

Recent·Most cited

Structure of dimerized assimilatory NADPH-dependent sulfite reductase reveals the minimal interface for diflavin reductase binding

Behrouz Ghazi Esfahani, Nidhi Walia, Kasahun Neselu, Yashika Garg, Mahira F. Aragon, Isabel Askenasy, Hui Alex Wei, Joshua H. Mendez, M. Elizabeth Stroupe

The paper determines the 2.78 Å resolution cryo-EM structure of Escherichia coli SiR, revealing the minimal interface for diflavin reductase binding and distinguishing between hemoprotein and ferredoxin partner interactions.

Nature Communications · Mar 26, 2025Peer-reviewedMolecular Biology

A structure-based mechanism for initiation of AP-3 coated vesicle formation

Matthew Begley, Mahira F. Aragon, Richard W. Baker

This study determines the structural mechanism of AP-3 membrane recruitment and activation through cryo-EM, revealing conformational changes driven by Arf1 binding and cargo engagement.

Proceedings of the National Academy of Sciences · Dec 20, 2024Peer-reviewedMolecular Biology

Smart Leginon enables cryoEM screening automation across multiple grids

Anjelique Sawh-Gopal, Aygul Ishemgulova, Eugene Y. D. Chua, Mahira F. Aragon, Joshua H. Mendez, Edward T. Eng, Alex J. Noble

This paper introduces Smart Leginon Autoscreen, an automated cryoEM grid screening system that reduces operator time from 6 hours to 10 minutes for 12 grids using machine learning and computer vision.

bioRxiv · Jul 24, 2023 · PreprintMolecular Biology