Diego E. B. Gomes

The paper investigates how anchor point selection affects the mechanical stability of an Affibody/PD-L1 complex using multiple experimental and computational methods.

The paper develops an integrated method combining dynamic network analysis with AI to predict epitopes in PD-L1:Affibody interactions, showing the perpendicular binding mode is more stable.

The paper evaluates AlphaFold's reliability in predicting mechanical properties of staph bacteria adhesins using in silico single-molecule force spectroscopy, showing high reliability for folds but limitations in complex predictions.