Author

Changze Han

University of IowaORCID 0000-0003-4863-2683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Organism:virus· 1

Frequent Co-Authors

Guiping HuiD· 2 shared Hillel HaimiD· 2 shared Mohammad FiliiD· 2 shared Alexa J. Kort· 1 shared Annika HelversoniD· 1 shared Benjamin W. DarbroiD· 1 shared Grant BrowniD· 1 shared Isaiah G. L. BicariD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBioinformatics

Guiping HuORCID

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2 papers

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedJun 10, 2024

Mutability Patterns Across the Spike Glycoprotein Reveal the Diverging and Lineage-specific Evolutionary Space of SARS-CoV-2.

Roberth Anthony Rojas Chávez, Mohammad Fili, Changze Han…·Hillel Haim

The paper identifies lineage-specific mutability patterns in SARS-CoV-2 spike protein to predict future mutations and guide vaccine/therapeutic design.

1 citation

virusproteomics

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BioinformaticsbioRxivPreprintJan 31, 2022

A New Classification Method Based on Dynamic Ensemble Selection and its Application to Predict Variance Patterns in HIV-1 Env

Mohammad Fili, Guiping Hu, Changze Han…·Hillel Haim

The paper introduces a dynamic ensemble selection method, KBC, to predict variance patterns in HIV-1 Env sequences and demonstrates its effectiveness in identifying clustered variance regions.

2 citations

humanDNA methylation

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