Author

Hillel Haim

University of IowaORCID 0000-0002-6071-5089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Organism:virus· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Guiping HuiD· 3 shared Mohammad FiliiD· 3 shared Aaron Nicholas GillmaniD· 2 shared Annika HelversoniD· 2 shared Cassian M Birler· 2 shared Changze HaniD· 2 shared Grant BrowniD· 2 shared Madeline M Broghammer· 2 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersBioinformatics

Guiping HuORCID

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Author profile →

4 papers

Recent·Most cited

Comprehensive Mapping of the Virus and Host Factors that Guide the Paths of HIV-1 Escape from a Therapeutic

Aaron Nicholas Gillman, Cassian M Birler, Rohith Rao Vujjini, Mohammad Fili, Samuel A McCarthy-Potter, Wilson Chen, Madeline M Broghammer, Guiping Hu, Margaret J. Gartland, Manyu Prakash, Annika Helverson, Grant Brown, Hillel Haim

The paper identifies HIV-1 mutations that confer resistance to temsavir and shows how mutation probability and host immunity influence their emergence in vivo.

Cell Reports · Jun 19, 2026Peer-reviewedMicrobiology

EZ-DMS - A Simple and Accessible Protocol and Software Package for Deep Mutational Scanning of Virus Proteins

Aaron Nicholas Gillman, Madeline M Broghammer, Samuel A McCarthy-Potter, Rohith Rao Vujjini, Cassian M Birler, Alex B. Kleinpeter, Hillel Haim

EZ-DMS provides a simple, cost-effective protocol and software for deep mutational scanning of HIV-1 Env protein variants, enabling analysis of amino acid fitness without bioinformatics expertise.

bioRxiv · Jan 2, 2026 · PreprintMicrobiology

Mutability Patterns Across the Spike Glycoprotein Reveal the Diverging and Lineage-specific Evolutionary Space of SARS-CoV-2.

Roberth Anthony Rojas Chávez, Mohammad Fili, Changze Han, Syed Ashiqur Rahman, Isaiah G. L. Bicar, S Gregory, Annika Helverson, Guiping Hu, Benjamin W. Darbro, Jishnu Das, Grant Brown, Hillel Haim

The paper identifies lineage-specific mutability patterns in SARS-CoV-2 spike protein to predict future mutations and guide vaccine/therapeutic design.

PLoS Computational Biology · Jun 10, 2024Peer-reviewedBioinformatics

A New Classification Method Based on Dynamic Ensemble Selection and its Application to Predict Variance Patterns in HIV-1 Env

Mohammad Fili, Guiping Hu, Changze Han, Alexa J. Kort, John Trettin, Hillel Haim

The paper introduces a dynamic ensemble selection method, KBC, to predict variance patterns in HIV-1 Env sequences and demonstrates its effectiveness in identifying clustered variance regions.

bioRxiv · Jan 31, 2022 · PreprintBioinformatics