Grant Brown

Comprehensive Mapping of the Virus and Host Factors that Guide the Paths of HIV-1 Escape from a Therapeutic

The paper identifies HIV-1 mutations that confer resistance to temsavir and shows how mutation probability and host immunity influence their emergence in vivo.

A double-blinded, placebo-controlled field trial of an OspA-based oral reservoir targeted vaccine against Borrelia burgdorferi

A field trial tested an OspA-based oral vaccine targeting reservoir mice, showing reduced tick infection rates and increased antibody levels in vaccinated mice.

Tick-borne coinfections modulate CD8+ T cell response and progressive leishmaniosis

The paper examines how tick-borne coinfections affect CD8+ T cell responses and disease progression in dogs with Leishmania infantum infection.

Mutability Patterns Across the Spike Glycoprotein Reveal the Diverging and Lineage-specific Evolutionary Space of SARS-CoV-2.

The paper identifies lineage-specific mutability patterns in SARS-CoV-2 spike protein to predict future mutations and guide vaccine/therapeutic design.

Inclusion of environmentally themed search terms improved Elastic Net regression nowcasts of regional Lyme disease rates

This study improves nowcasting of Lyme disease rates using Elastic Net regression with environmentally themed search terms from Google Trends.