Author

Helen B Belato

Brown UniversityORCID 0000-0003-4900-8698Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

Alexa L KnightiD· 2 shared Chinmai PindiiD· 2 shared G. JogliD· 2 shared George P. LisiiD· 2 shared Giulia PalermoiD· 2 shared Alexandra M. D’OrdineiD· 1 shared Briana J. MercadoiD· 1 shared Charlotte S Dresser· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiophysics

Alexa L KnightORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintApr 9, 2026

Orthosteric and allosteric effects of anti-CRISPR II-C1 inhibition on GeoCas9 from integrated structural biophysics

Alexa L Knight, Helen B Belato, Charlotte S Dresser…·George P. Lisi

This study investigates how AcrIIC1 inhibits GeoCas9 by analyzing structural and dynamic changes in the HNH nuclease domain.

DOI 10.64898/2026.04.08.717222

structural biologyexperimental assay

𝕏 PostBluesky

BiophysicseLifePeer-reviewedJul 16, 2024

Structural and Dynamic Impacts of Single-atom Disruptions to Guide RNA Interactions within the Recognition Lobe of Geobacillus stearothermophilus Cas9

Helen B Belato, Alexa L Knight, Alexandra M. D’Ordine…·George P. Lisi

This study investigates how single-atom mutations in the recognition lobe of GeoCas9 affect its structure, dynamics, and guide RNA interactions without altering its functional specificity.

5 citations

bacteria (other)protein structure

𝕏 PostBluesky