Author

Carolyn G. Chen

Duke UniversityORCID 0000-0003-4933-6544Unclaimed ORCID profile · follow to get notified of new preprints

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Carolyn G. Chen1 paper

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Carlos Montes· 1 shared Claudia P. González-HuntiD· 1 shared Elise FouquereliD· 1 shared Ivana BarrazaiD· 1 shared Jennifer LiuiD· 1 shared Laurie H. SandersiD· 1 shared Lingyan Ma· 1 shared Natalie R. GassmaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Carlos Montes

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintMar 1, 2026

Parkinson's disease linked LRRK2 G2019S drives oxidative nuclear DNA damage and PARP1 hyperactive signaling

Jennifer Liu, Claudia P. González-Hunt, Tara Richbourg…·Laurie H. Sanders

This study shows that the LRRK2 G2019S mutation causes oxidative nuclear DNA damage and PARP1 hyperactivation, leading to cellular vulnerability in Parkinson's disease.

DOI 10.64898/2026.02.27.708379

humanDNA methylation

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