Author

Tara Richbourg

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Laurie H. SandersiD· 3 shared Claudia P. González-HuntiD· 2 shared Ivana BarrazaiD· 2 shared Alex George· 1 shared Anas BitariD· 1 shared Andrew B. WestiD· 1 shared Carlos Montes· 1 shared Carolyn G. CheniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCell Biology

Laurie H. SandersORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rab12 is a regulator of mitophagy and mitochondrial homeostasis

Tara Richbourg, Alex George, Anas Bitar, Ian T. Ryde, Casey Farrell, Tuyana B. Malankhanova, Jennifer Liu, Silas A. Buck, Ivana Barraza, So Young A Kim, Xiaoyan Nie, Andrew B. West, Joel N. Meyer, Laurie H. Sanders

This study identifies Rab12 as a negative regulator of mitophagy and mitochondrial homeostasis, showing its loss increases mitochondrial clearance and sensitivity to stress.

bioRxiv · Mar 31, 2026 · PreprintCell Biology

Parkinson's disease linked LRRK2 G2019S drives oxidative nuclear DNA damage and PARP1 hyperactive signaling

Jennifer Liu, Claudia P. González-Hunt, Tara Richbourg, Ivana Barraza, Carolyn G. Chen, Carlos Montes, Lingyan Ma, Ruihua Cao, Vishruth Hanumaihgari, Natalie R. Gassman, Elise Fouquerel, Laurie H. Sanders

This study shows that the LRRK2 G2019S mutation causes oxidative nuclear DNA damage and PARP1 hyperactivation, leading to cellular vulnerability in Parkinson's disease.

bioRxiv · Mar 1, 2026 · PreprintCell Biology

G2019S selective LRRK2 kinase inhibitor abrogates mitochondrial DNA damage

Nicholas Pena, Tara Richbourg, Claudia P. González-Hunt, Rui Qi, Paul B. Wren, Carrolee Barlow, Natalie F. Shanks, Holly J. Carlisle, Laurie H. Sanders

The paper tests a G2019S selective LRRK2 inhibitor, EB-42168, showing it reduces mtDNA damage in G2019S models and patient cells better than a non-selective inhibitor.

npj Parkinson s Disease · Mar 1, 2024Peer-reviewedNeuroscience