Author

Natalie R. Gassman

University of Alabama at BirminghamORCID 0000-0002-8488-2332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Carlos Montes· 1 shared Carolyn G. CheniD· 1 shared Claudia P. González-HuntiD· 1 shared Dena FridmaniD· 1 shared Elise FouquereliD· 1 shared Hila Sharim· 1 shared Ivana BarrazaiD· 1 shared Jennifer LiuiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCell Biology

Carlos Montes

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Parkinson's disease linked LRRK2 G2019S drives oxidative nuclear DNA damage and PARP1 hyperactive signaling

Jennifer Liu, Claudia P. González-Hunt, Tara Richbourg, Ivana Barraza, Carolyn G. Chen, Carlos Montes, Lingyan Ma, Ruihua Cao, Vishruth Hanumaihgari, Natalie R. Gassman, Elise Fouquerel, Laurie H. Sanders

This study shows that the LRRK2 G2019S mutation causes oxidative nuclear DNA damage and PARP1 hyperactivation, leading to cellular vulnerability in Parkinson's disease.

bioRxiv · Mar 1, 2026 · PreprintCell Biology

Apurinic/apyrimidinic endodeoxyribonuclease 2 (APEX2/APE2) is required for efficient expression of TERT in human embryonic stem cells.

Josh Lewis Stern, Lindsay F. Rizzardi, Natalie R. Gassman

This study shows APEX2 is essential for TERT expression in hESCs and a melanoma cell line, with APEX2 knockdown reducing telomerase activity and affecting other genes, particularly those with repetitive DNA sequences.

bioRxiv · Sep 23, 2024 · PreprintCell Biology

Genome wide mapping of DNA lesions by Repair Assisted Damage Detection sequencing - RADD-Seq

Noa Gilat, Dena Fridman, Hila Sharim, Sapir Margalit, Natalie R. Gassman, Yael Michaeli, Yuval Ebenstein

The paper introduces RADD-Seq, a method to map DNA damage and repair sites genome-wide, showing oxidative damage distribution and repair prioritization in human cells.

bioRxiv · Feb 7, 2021 · PreprintGenomics