Author
Princess Máxima CenterORCID 0000-0003-4986-1656Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Vassilena Sharlandjieva, Catherine Chahrour, Frederik Heymann Lassen…·Thomas A. Milne
The paper investigates Menin's role in enhancer-promoter interactions in MLL-rearranged and NPM1c leukemia models, finding context-dependent effects on transcriptional regulation and enhancer function.
Alastair Smith, Nicholas Denny, Catherine Chahrour…·Thomas A. Milne
This study identifies enhancer heterogeneity as a driver of transcriptional differences in KMT2A::AFF1 ALL patients, revealing patient-specific enhancer activity at oncogenes.
Christina Stangl, Sam de Blank, Ivo Renkens…·Glen R. Monroe
This paper introduces FUDGE, a method for detecting fusion genes using CRISPR/Cas9 enrichment and long-read sequencing, achieving high sensitivity and specificity across various cancer types.