Author

Christina Stangl

Utrecht University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:variant calling· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:long-read sequencing· 1 Approach:machine learning (classical)· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Ivo Renkens· 2 shared Jose Espejo Valle-InclániD· 2 shared Markus J. van RoosmaleniD· 2 shared Sam de BlankiD· 2 shared Wigard P. KloostermaniD· 2 shared Anouk C. de JongiD· 1 shared Anton George HensseniD· 1 shared Chris J. de WitteiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Ivo Renkens

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2 papers

Recent·Most cited

Rapid identification of genomic structural variations with nanopore sequencing enables blood-based cancer monitoring

Jose Espejo Valle-Inclán, Christina Stangl, Anouk C. de Jong, Lisanne F. van Dessel, Markus J. van Roosmalen, Jean Helmijr, Ivo Renkens, Roel Janssen, Sam de Blank, Chris J. de Witte, John W.M. Martens, Maurice P.H.M. Jansen, Martijn P. Lolkema, Wigard P. Kloosterman

SHARC rapidly identifies somatic genomic structural variations from nanopore sequencing for blood-based cancer monitoring, detecting ten SVs per sample and enabling treatment response tracking in metastatic prostate cancer.

Genome Medicine · May 18, 2021Peer-reviewedGenetic & Genomic Medicine

Partner-independent fusion gene detection by multiplexed CRISPR/Cas9 enrichment and long-read Nanopore sequencing

Christina Stangl, Sam de Blank, Ivo Renkens, Liset Westera, Tamara C. A. I. Verbeek, Jose Espejo Valle-Inclán, Rocío Chamorro González, Anton George Henssen, Markus J. van Roosmalen, Ronald W. Stam, Emile E. Voest, Wigard P. Kloosterman, Gijs W van Haaften, Glen R. Monroe

This paper introduces FUDGE, a method for detecting fusion genes using CRISPR/Cas9 enrichment and long-read sequencing, achieving high sensitivity and specificity across various cancer types.

Nature Communications · Jun 5, 2020Peer-reviewedGenomics