ImmunologyPLoS ONEPeer-reviewed
In vitro detection of canine anti-human antibodies following intratumoral injection of the hu14.18-IL2 immunocytokine in spontaneous canine melanoma
Andrew T. Kosharek, Cindy Zuleger, William S. Glass…·Mark R. Albertini
The paper detects canine anti-human antibodies (CAHA) in dogs treated with hu14.18-IL2 immunocytokine, showing increased levels and binding inhibition post-treatment.
DOI 10.1371/journal.pone.0330200