Mark R. Albertini

This study examines the effects of GPI-deficiency on TCR, CD3, CD28 expression and IL-2 production in a GPI-deficient Jurkat T cell line, finding altered surface receptor expression but no significant impairment in IL-2 production under direct pathway activation.

The paper detects canine anti-human antibodies (CAHA) in dogs treated with hu14.18-IL2 immunocytokine, showing increased levels and binding inhibition post-treatment.