Author

Emma Grunkemeyer

University of IowaORCID 0009-0000-2756-1455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jan S. FassleriD· 2 shared David G Cooper· 1 shared David G. CooperiD· 1 shared Shulin LiuiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersGenomics

Jan S. FasslerORCID

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2 papers

Recent·Most cited

GenomicsMicrobial GenomicsPeer-reviewedSep 3, 2026

Transcriptomic shift in ethanol and amino acid metabolic genes regulated by Med15 during alcoholic fermentation

David G Cooper, Emma Grunkemeyer, Jan S. Fassler

This study shows that Med15 variants from wine yeast enhance fermentation efficiency by upregulating glycolytic, fermentation, and amino acid biosynthesis genes.

DOI 10.1099/mgen.0.001811

yeastbulk RNA-seq

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Molecular BiologyMolecular and Cellular BiologyPeer-reviewedDec 24, 2024

The role of Med15 sequence features in transcription factor interactions

David G. Cooper, Shulin Liu, Emma Grunkemeyer, Jan S. Fassler

This study investigates how sequence features of Med15, particularly polyglutamine tracts and activator binding domains, influence its activity and interactions with transcription factors.

5 citations

yeastexperimental assay

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