Ruixi Li

The paper presents an xQTL atlas of regulatory variation in the aging human brain, integrating multiple modalities and cell types across four studies, identifying more variant-molecular-trait associations by including TAD boundaries.

This paper links molecular mechanisms to Alzheimer's disease and aging by integrating neuroimaging endophenotypes with molecular quantitative trait loci.

SuSiE 2.0 improves genetic fine-mapping and phenotype prediction with faster performance, better calibration, and new methods like SuSiE-ash.

The paper modifies the SuSiE model to improve calibration in small-sample studies, reducing false positives in genetic fine-mapping.