Author

Arni Thorlacius

Uppsala UniversityORCID 0009-0000-3524-4142Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anna SundborgeriD· 2 shared Maksim RuleviD· 1 shared Oscar SundbergiD· 1 shared Shu-Chieh Susie ChangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersBiophysics

Anna SundborgerORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJun 25, 2026

Endophilin B1 primes mitochondria for execution

Shu-Chieh Susie Chang, Arni Thorlacius, Anna Sundborger

This study identifies endophilin B1 as a membrane remodeling protein that primes mitochondria for Bax-mediated permeabilization during apoptosis.

DOI 10.64898/2026.06.25.733981

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

BiochemistryCommunications BiologyPeer-reviewedFeb 5, 2025

Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers

Arni Thorlacius, Maksim Rulev, Oscar Sundberg, Anna Sundborger

This study presents the highest resolution cryo-EM structure of a BAR protein and shows endophilin B1 permeabilizes liposomes containing cardiolipin, proposing a new model for Bax-mediated cell death.

5 citations

cryo-EMdeep learning

𝕏 PostBluesky