Author

Hanping Wang

Peking UniversityORCID 0009-0000-3986-5608Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Fanhao WangiD· 1 shared Luhua LaiiD· 1 shared Qi SuniD· 1 shared Ruoyao Xiong· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Fanhao WangORCID

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1 paper

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BiophysicsbioRxivPreprintNov 26, 2025

FuzzAletheia: Mapping dynamic interaction landscapes of intrinsically disordered protein-ligand complexes to accelerate ligand optimization

Hanping Wang, Fanhao Wang, Ruoyao Xiong…·Luhua Lai

FuzzAletheia maps dynamic interaction patterns of IDP-ligand complexes to guide hit-to-lead optimization, achieving a 10-fold activity enhancement in a p53 ligand.

DOI 10.1101/2025.11.26.690418

humanproteomics

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