Author

Fanhao Wang

Peking UniversityORCID 0009-0006-6683-4720Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Luhua LaiiD· 2 shared Changsheng ZhangiD· 1 shared Hanping WangiD· 1 shared Jintao ZhuiD· 1 shared Qi SuniD· 1 shared Ruoyao Xiong· 1 shared Tiantian ZhangiD· 1 shared Xiaoling ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

Luhua LaiORCID

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintNov 26, 2025

FuzzAletheia: Mapping dynamic interaction landscapes of intrinsically disordered protein-ligand complexes to accelerate ligand optimization

Hanping Wang, Fanhao Wang, Ruoyao Xiong…·Luhua Lai

FuzzAletheia maps dynamic interaction patterns of IDP-ligand complexes to guide hit-to-lead optimization, achieving a 10-fold activity enhancement in a p53 ligand.

DOI 10.1101/2025.11.26.690418

humanproteomics

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BiochemistrybioRxivPreprintJan 18, 2025

Target-based de novo design of cyclic peptide binders

Fanhao Wang, Tiantian Zhang, Jintao Zhu…·Luhua Lai

This paper introduces CYC_BUILDER, a reinforcement learning method for designing cyclic peptides that bind target proteins, demonstrating its effectiveness in generating potent inhibitors for TNF.

3 citations

protein structuredeep learning

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